"0280-0121-01" National Drug Code (NDC)

NDC Code	0280-0121-01
Package Description	12 POUCH in 1 CARTON (0280-0121-01) / 2 TABLET, EFFERVESCENT in 1 POUCH
Product NDC	0280-0121
Product Type Name	HUMAN OTC DRUG
Proprietary Name	Alka-seltzer Plus Severe Cold Night Powerfast Fizz
Non-Proprietary Name	Aspirin, Chlorpheniramine Maleate, Dextromethorphan Hydrobromide, Phenylephrine Bitartrate
Dosage Form	TABLET, EFFERVESCENT
Usage	ORAL
Start Marketing Date	20230524
Marketing Category Name	OTC MONOGRAPH FINAL
Application Number	part341
Manufacturer	Bayer HealthCare LLC.
Substance Name	ASPIRIN; CHLORPHENIRAMINE MALEATE; DEXTROMETHORPHAN HYDROBROMIDE; PHENYLEPHRINE BITARTRATE
Strength	325; 2; 10; 7.8
Strength Unit	mg/1; mg/1; mg/1; mg/1
Pharmacy Classes	Adrenergic alpha1-Agonists [MoA], Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA], alpha-1 Adrenergic Agonist [EPC]